Pharmacological Potential of Tradescantia zebrina Leaf Extracts

Periodo de realización: 1900/01/01 al 2020/01/01

Tipo: Artículo científico

Resumen: "lants are good sources of bioactive compounds, including phenolic compounds, recognized for their antioxidant properties. Tradescantia zebrina (matalí) is common plant in the southern region of Mexico recognized in traditional medicine for its pharmacological properties, however there is little scientific evidence to support them. The objective of the present study was to evaluate the in vitro pharmacological potential of ethanolic and aqueous extracts from the leaves of T. zebrina. The antioxidant activity by ABTS+ , DPPH+ radicals scavenger, chelating activity of Cu+ and reducing power of Fe+ , the anti-inflammatory and antimicrobial activity of the extracts were determined. A one-way analysis of variance and a Tukey range test were performed to determine the differences between the extracts. The ethanolic extract presented the highest content of phenolic compounds (70.2 ± 1.2 mg gallic acid equivalents) and had the best capacity to neutralize DPPH+ radicals (~84%), it can be determined that it can protect by 44.5% inhibition of the protein denaturation. In aqueous extractions, the maceration extract obtained the highest concentration of flavonoids (27.8 ± 1.5 5 mg gallic acid equivalents) and presented a high protection against protein denaturation (85.46%). With the infusion, a greater Fe+ reducing power (77%) and a greater capacity to chelate Cu (60%) are compared to the other two extracts. No antimicrobial effects were detected with the modifications of the extracts tested against the studied strains. T. zebrina showed a high content of antioxidants and antioxidant activity, the infusion showed greater activity in the inhibition of albumin denaturation, which could have a possible anti-inflammatory effect. This information helps to support some of the medicinal properties traditionally attributed to it, more studies are still needed."

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