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Genotoxicological response of the common Carp (Cyprinus carpio) Exposed to Spring Water in Tlaxcala, México

Cita: García-Nieto E, Juárez-Santacruz L, Torres-Dosal A. 2014. Genotoxicological response of the common Carp (Cyprinus carpio) Exposed to Spring Water in Tlaxcala, México. Bulletin of Environmental Contamination and Toxicology. DOI:10.1007/s00128-014-1318-2.
En: Bulletin of Environmental Contamination and Toxicology. Vol. , no. (2014)
ISSN: 0007-4861

Fecha de realización: 2014/05/31

Tipo: Artículo con arbitraje

Resumen: "This study evaluated the genotoxic impact of anthropic activities in Huactzinco Spring, using Cyprinus carpio as a biomonitor. In situ and in vivo experimental designs were compared by means of simultaneous 2-week exposures. The water from the spring generated mean micronuclei frequency values (108.6 ± 32 MN/1,000) and DNA fragmentation values (143.4 ± 35 au) which were statistically higher than those for the negative control (10.9 ± 6 MN/1,000 and 67.6 ± 23 au). The in situ and in vivo experiments supported one another. The comet assay proved to be the most sensitive test, with an EC50 value (11.4 % ± 3.4 %) being less than that determined for the micronuclei test (54.8 % ± 3.2 %). The results of this study confirm the usefulness of C. carpio as an environmental contamination biomonitor, and suggest that Huactzinco Spring water constitutes a latent risk to human health and the environment. "

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